About Bonnie Doran

I'm a writer. My heart is in science fiction, but I sold sixty-seven devotions before I wrote novels. My debut novel, a science thriller entitled Dark Biology, was published with Harbourlight, an imprint of Pelican Book Group. I'm also a cancer survivor, diagnosed with malignant melanoma in 2014. I am currently working on a devotional book for cancer survivors. When I'm not writing, I enjoy reading, old sci-fi movies, cooking, Sudoku puzzles, Scrabble, and hanging out with writers and sci-fi fans. I have a reputation for telling groan-producing puns. I've been married 35 years to John, an electrical engineer and Mad Scientist who plays with lasers for a living. We are owned by two Siamese cats.

Hitting the Target in Pancreatic Cancer

Pancreatic cancer is one of the hardest to treat. However, three independent studies suggest a way.

Pancreatic cancer

Researchers are conducting clinical trials that use two drugs in tandem to thwart a mutated gene KRAS, that drives tumor growth in 95% of patients with pancreatic cancer.

KRAS is one of the most elusive targets in cancer research. This is because the KRAS protein lacks places where a small-molecule drug can bind and impair its function.

Mutant KRAS produce continuous growth signals, passed from one protein to the next, that results in a chain reaction called a signaling pathway. Over six of these pathways stem from KRAS. If one is impaired, the others can pick up the slack.

Researchers found that by eliminating the autophagy pathway that provides energy for the cancer cells at the same time that another drug indirectly targets KRAS, they can shrink pancreatic cancer tumors in mice. This is huge because the KRAS gene is mutated in 30% of all cancers, including some types of colorectal and lung cancer.

One clinical trial to explore this treatment is already enrolling participants. A second is expected to launch in the near future.

For more information, see National Cancer Institute http://www.NationalCancerInstitute.org

 

The Hair Thing

Hair loss can be traumatic for cancer patients. I didn’t lose all my hair after immunotherapy, but it was getting so thin that I debated whether to go bald, wear a scarf, or invest in a wig.

Cancer Patient Deals With Hair Loss

A wig can cost from forty to thousands of dollars. A number of organizations offer free wigs and scarves for cancer patients who have lost their hair due to chemotherapy or radiation. Here are a few:

Friends Are By Your Side provides free wigs for women and children facing cancer all over the world. Check for the salon nearest you. They also provide styling services to help women feel in control of their appearance. 

Lolly’s Locks believes that looking good can help you feel good. They provide high-quality stylized wigs and even customized wigs free of cost. They have donated wigs to women in 47 states. 

The American Cancer Society accepts wig donations, which are collected for wig banks at their local chapters. Some wigs are distributed through ACS and some through local Look Good Feel Better meetings.

CancerCare is another source as part of their Women’s Cancer Program.

Some local affiliates of Susan G. Komen provide free wigs. 

Also, many cancer centers take donated wigs and make them available free of cost to those beginning breast cancer treatment. 

If you decide to wear a wig, go for it. Take advantage of these organizations and boost your self-confidence.